Chemistry (CHEM)

CHEM 100  Introductory Chemistry  (4 credits)

An introductory lecture and laboratory course in modern chemistry for non-science majors intended to make chemistry understandable, accessible and applicable. Topics include atomic theory, stoichiometry, bonding, molecular shapes, acid-base theory, ploymers, medicine, and nutrition. Meets Gen Ed - Natural Science Laboratory.

CHEM 105  Basic Chemistry  (3 credits)

Restriction(s): Restricted to students of the Health Careers Program. This course will introduce the basic concepts of chemistry.

CHEM 106  Principles of Chemistry  (3 credits)

Prerequisite(s): Score of 14 or less on the Chemistry Readiness Test; and MATH 100 or MATH 111 with a grade of C- or better OR placement in a higher level Calculus course (MATH 122, MATH 221, MATH 222, AMAT 120, AMAT 220); students with a score of 11, 12, 13 or 14 on the Chemistry Readiness Test can take MATH 100 or MATH 111 as a co-requisite.  A one-semester introductory lecture in the application of algebra and numerical methods in general chemistry. This course is recommended for students who have no or a weak background in chemistry and are required to complete general chemistry coursework for their major. All students who do not get a satisfactory score on department's General Chemistry Readiness Test must complete this course before they can enroll in General Chemistry I (CHEM 120). This course does not meet any General Education requirements.

CHEM 113  Fundamentals of Chemistry  (4 credits)

A one semester introductory lecture and laboratory course in the fundamental concepts of chemistry. This course is suitable for students who have no prior background in chemistry. It is intended for students majoring in Food and Nutrition and other non-science majors. Some aspects of the course are quantitative, and a background in algebra is assumed. This course prepares students to proceed to CHEM 130 Fundamentals of Organic Chemistry. Meets Gen Ed - Natural Science Laboratory.

CHEM 114  Fundamentals of Chemistry for Nursing  (3 credits)

Restriction(s): Nursing majors only. A one semester introductory lecture course in the fundamental concepts of chemistry. This course restricted to students who are Nursing majors. Some aspects of the course are quantitative, and a background in algebra is assumed.

CHEM 120  General Chemistry I  (4 credits)

Prerequisite(s): MATH 100 or MATH 111 may be taken as prerequisite or corequisite with a grade of C- or better OR placement in a higher level Calculus course (MATH 122, MATH 221, MATH 222, AMAT 120, AMAT 220); and satisfactory score on the Chemistry readiness test or CHEM 105 or CHEM 106 with a grade of C- or better. Introductory lecture and laboratory course for science majors, prerequisite for all advanced chemistry courses. Introduction to atomic and molecular structure, bonding, stoichiometry, states of matter, solutions, and selected topics in descriptive inorganic chemistry. Laboratory stresses techniques and data treatment and their use in examining chemical systems. Meets Gen Ed - Natural Science Laboratory.

CHEM 121  General Chemistry II  (4 credits)

Prerequisite(s): CHEM 120 with a grade of C- or higher. Introductory lecture and laboratory course for science majors, prerequisite for all advanced chemistry courses. Introduction to thermochemistry, kinetics; general acid base, precipitation, redox equilibria, electrochemistry and selected topics in descriptive inorganic chemistry. Laboratory stresses techniques and data treatment and their use in examining chemical systems.

CHEM 130  Fundamentals of Organic Chemistry  (4 credits)

Prerequisite(s): CHEM 113 with a grade of C- or higher. Survey of organic chemistry covering all major classes, nomenclature, and characteristic class reactions.

CHEM 190  Freshman Seminar in Chemistry  (1 credit)

An experience for freshmen majoring in chemistry and biochemistry that will help them to succeed in their major by learning study skills and becoming acquainted with the culture of higher education. Meets Gen Ed - New Student Seminar.

CHEM 195  Problem Solving-General Chemistry  (1 credit)

Course designed to help students in application of mathematics in chemistry with emphasis on individual needs.

CHEM 199  Laboratory Project  (1-3 credits)

Prerequisite(s): CHEM 120 or equivalent and permission of department. Independent laboratory work in chemistry under the guidance of a faculty mentor.

CHEM 220  Descriptive Inorganic Chemistry  (3 credits)

Prerequisite(s): CHEM 121 with a grade of C- or higher. Introduction to the descriptive inorganic chemistry of the chemical elements and selected compounds excluding hydrocarbons and their derivatives. The periodic table and periodic relationships among the elements will be used as an organizing tool to explore the sources, properties, compounds, reactions, and industrial uses of the chemical elements. The primary emphasis will be on the main group elements, but transition metal chemistry will also be described. Selected applications of inorganic substances in biochemistry, environmental chemistry, industrial chemistry, material science, and medicine will be discussed.

CHEM 230  Organic Chemistry I  (3 credits)

Prerequisite(s): CHEM 121 with a grade of C- or higher. Structure and bonding in organic compounds: nomenclature, reactions, properties, and aromatic compounds: stereochemistry; structure analysis by IR, NMR, UV, and MS; introduction to molecular orbital theory.

CHEM 231  Organic Chemistry II  (3 credits)

Prerequisite(s): CHEM 230 with a grade of C- or higher. Nomenclature, reactions, properties, and synthesis of ethers, epoxides, alcohols, amines, and carbonyl compounds; carbohydrates; amino acids, peptides and proteins; pericyclic reactions; synthetic polymers.

CHEM 232  Experimental Organic Chemistry I  (2 credits)

Prerequisite(s): CHEM 230 is a prerequisite or corequisite. A laboratory course to be taken concurrently with CHEM 230. Basic techniques for the separation, analysis and synthesis of organic compounds: recrystallization, distillation, extraction, GC, HPLC, TLC, GC/MS, IR, H/C13- NMR, chemical safety methods and regulations.

CHEM 233  Experimental Organic Chemistry II  (2 credits)

Prerequisite(s): CHEM 231 may be taken as prerequisite or corequisite; and CHEM 232 with a grade of C- or higher. A laboratory course to be taken concurrently with CHEM 231 and after completion of CHEM 232. Basic techniques for organic synthesis, mechanistic studies, separation and analysis, and chemical safety: multistep syntheses, spectral data-base searching, phase-transfer catalysis, anhydrous procedures, analysis of unknowns by wet-chemical and spectral methods.

CHEM 270  Fundamentals of Biochemistry  (5 credits)

Prerequisite(s): CHEM 130 with a grade of C- or higher. Structure and function of the biomolecules and the metabolic interrelationships in the cell. Primarily for foods and nutrition majors.

CHEM 310  Analytical Chemistry  (4 credits)

Prerequisite(s): CHEM 230 with a C- or better OR concurrent enrollment in CHEM 230 OR concurrent enrollment in CHEM 220. Introduction to the principles, applications, and lab work of analytical chemistry including fundamental concepts in both qualitative and quantitative chemical analysis. Topics include systematic treatment of equilibria, chemical measurements, classical methods of analysis, analytical spectroscopy, electrochemical methods, and chromatographic methods. Analysis of data is introduced, including, errors and uncertainty in measurements, error propagation and uncertainty analysis.

CHEM 320  Environmental Chemical Analysis  (3 credits)

Prerequisite(s): CHEM 230 and CHEM 232 with a grade of C- or higher. A study of the sources, reactions, transport, effects, and fates of chemical species in the environment. Lecture and lab will stress the theory, methodology, techniques, and instrumentation for air, water and soil analysis for contaminants.

CHEM 325  Atmospheric Chemistry  (3 credits)

Prerequisite(s): CHEM 230 and CHEM 232 with a grade of C- or higher. Atmospheric chemistry of the major pollutants of concern in today's environment, the emission sources, air/water and air/soil partitioning and exchange, atmospheric transport pathway, transformation processes (biological degradation, hydrolysis, photochemical transformations), deposition processes, pollutant chronic and acute health impacts, prevention and regulation. Course requirements: 2 field trips.

CHEM 330  Green Chemistry  (3 credits)

Prerequisite(s): CHEM 231 with a grade of C- or higher. The focus of the course will be on the principles and applications of Green Chemistry, and its potential role in the minimization or elimination of negative impacts on the environment by the chemical industry, and the establishment of safe chemical practices. Topics such as, catalysis, development of more environmentally friendly and sustainable chemical processes and industrial case studies will be discussed.

CHEM 340  Physical Chemistry I  (3 credits)

Prerequisite(s): CHEM 231 and PHYS 192 and MATH 221 with a grade of C- or higher. Thermodynamics, homogeneous and heterogeneous equilibria, gases, electrochemistry, solutions, colligative properties.

CHEM 341  Physical Chemistry II  (3 credits)

Prerequisite(s): CHEM 340 with a grade of C- or higher. Kinetics, photochemistry, molecular physical chemistry.

CHEM 343  Experimental Physical Chemistry  (2 credits)

Corequisite(s): CHEM 341. Prerequisite(s): CHEM 340 with a grade of C- or higher. A laboratory course to be taken concurrently with CHEM 341. Application and experience with experimental techniques of physical chemistry. Students will perform experiments in calorimetry, measurement of thermodynamic variables, electro-chemical phenomena and kinetics. Analysis of experimental data, statistics and applications of microcomputers will be included. Meets the Graduation Writing Requirement for majors in Chemistry.

CHEM 347  Biophysical Chemistry  (3 credits)

Prerequisite(s): CHEM 370 with a grade of C- or higher and CHEM 340 with a grade of C- or higher. Thermodynamics, equilibria, transport processes, kinetics, and electrochemistry as applied to biomolecules and cellular processes.

CHEM 370  Biochemistry I  (3 credits)

Prerequisite(s): CHEM 231 with a grade of C- or higher. Organization of the living cell; structure, function and chemistry of proteins, carbohydrates and lipids; bioenergetics and oxidation.

CHEM 371  Biochemistry II  (3 credits)

Prerequisite(s): CHEM 370 with a grade of C- or higher. The second semester of a two semester course in biochemistry. The course continues the coverage of the chemistry of proteins, carbohydrates, lipids, and nucleic acids, and their role in cellular function and processes. Topics such as the chemistry of hormones, recombinant DNA, mechanisms of enzyme action, protein synthesis, immunoglobulins and membranes are included.

CHEM 372  Experimental Biochemistry I  (2 credits)

Prerequisite(s): CHEM 231 with a grade of C- or higher and CHEM 232 with a grade of C- or higher and CHEM 370 may be taken as prerequisite (with a grade of C- or higher) or corequisite. A lecture and laboratory course of experimental methods in biochemistry. Biochemical applications of spectroscopy, chromatographic methods, enzyme kinetics, DNA and protein purification and electrophoretic techniques.

CHEM 373  Experimental Biochemistry II  (4 credits)

Corequisite(s): CHEM 371. Prerequisite(s): CHEM 310 with a grade of C- or higher, CHEM 370 with a grade of C- or higher, and CHEM 372 with a grade of C- or higher. A second-semester laboratory in modern techniques in experimental biochemistry to include important applications of major instrumentation. Culminates with a student-designed biochemical research project. Primarily intended for Biochemistry majors.

CHEM 410  Instrumental Analysis  (5 credits)

Prerequisite(s): CHEM 310 with a grade of C- or higher and CHEM 340 with a grade of C- or higher. Introduction to application of instrumental methods of analytical chemistry. Instrument techniques studied will include absorbance and fluorescence spectroscopy, infrared spectroscopy, atomic absorption spectroscopy, liquid and gas chromatography and mass spectrometry. Additional topics such as nuclear magnetic resonance spectroscopy and electrochemistry may also be covered. Theory and application will be examined in lecture and laboratory. Equivalent course CHEM 311 effective through Winter 2024.

CHEM 420  Advanced Inorganic Chemistry  (3 credits)

Prerequisite(s): CHEM 340 is a prerequisite or corequisite. Physical basis of bonding and reactivity of inorganic compounds. Electronic structure of atoms, ionic and covalent bonding, symmetry properties, chemistry and structure of transition metal compounds, organometallic chemistry, introduction to solid-state structures.

CHEM 421  Experimental Inorganic Chemistry  (3 credits)

Corequisite(s): CHEM 420. Prerequisite(s): CHEM 310. Experience utilizing a broad selection of modern techniques for the synthesis, characterization and chemistry of inorganic compounds. Subjects covered will include catalysis, reaction mechanisms, and use in organic synthesis.

CHEM 430  Advanced Organic Chemistry  (3 credits)

Prerequisite(s): CHEM 340 or CHEM 370. Consideration of structural and electronic theories which form the basis of organic chemistry.

CHEM 440  Advanced Physical Chemistry  (3 credits)

Prerequisite(s): MATH 325 and CHEM 341. Quantum mechanics, bonding theory, atomic structure, statistical thermodynamical calculations.

CHEM 490  Special Topics in Chemistry  (2-3 credits)

Prerequisite(s): CHEM 340 or CHEM 370. In-depth study of a modern aspect of chemistry. May be repeated once for a maximum of 6 credits as long as the topic is different.

CHEM 491  Honors Seminar in Chemistry  (2 credits)

Prerequisite(s): Admission to the honors program in chemistry or permission of the chemistry honors committee. Seminars and discussions on selected areas in chemistry under faculty guidance for students enrolled in the honors program in chemistry.

CHEM 492  Honors Thesis in Chemistry  (2 credits)

Prerequisite(s): CHEM 491. Preparation and oral presentation of a comprehensive written thesis in chemistry under guidance of a faculty mentor for completion of the honors program in chemistry.

CHEM 495  The Chemical Literature  (1 credit)

Prerequisite(s): CHEM 340 or CHEM 370 may be taken as prerequisite or corequisite. Introduction to web-based searching of the chemical and biochemical literature databases, including Scifinder Sholar, Science Citation Index, Science Direct, and ACS Search. Course requirements include a literature search paper and a brief seminar. Meets the Graduation Writing Requirement for majors in Chemistry.

CHEM 496  Biochemistry Literature  (1 credit)

Corequisite(s): CHEM 371. Prerequisite(s): CHEM 370. Introduction to searching the biochemistry literature including computerized searches and exploration of on-line journals and interesting internet sites. After becoming familiar with modern methods of information retrieval, students will conduct individual literature searches and do a group presentation.

CHEM 498  Senior Laboratory  (3 credits)

Prerequisite(s): CHEM 311, and CHEM 341, and CHEM 343. Multi-disciplinary laboratory study of the synthesis, separation, and characterization of chemical compounds.

CHEM 499  Undergraduate Research  (1-3 credits)

Prerequisite(s): CHEM 233 and departmental approval. Laboratory research on a specific problem in chemistry under guidance of a faculty mentor.

CHEM 501  Teaching Chemistry in the Secondary School  (3 credits)

Prerequisite(s): 16 semester hours in chemistry. Study of objectives, recent trends, methods of presentation, courses of study, lesson planning, instructional aids, and subject matter of high school chemistry.

CHEM 504  Chemistry for Middle Grade Teaching  (4 credits)

Restriction(s): Majors in Elementary School with Subject Matter Specialization: Science 5-8 or program coordinator approval. This course will provide concepts and learning activities in Chemistry for middle school teachers. Emphasis will be on examining changes of state, solutions, and simple chemical reactions. These teachers will develop the knowledge and experience that will allow them to define the properties of chemical compounds and elements. Laboratory investigations of the properties of substances and their changes through various chemical interactions will provide a basis for the high school student to understand diverse types of chemical reactions and their applications. Equivalent course SCIM 504 effective through Summer 2019.

CHEM 510  Hazardous Materials Management  (3 credits)

Prerequisite(s): CHEM 230 or equivalent. Restriction(s): Majors in College of Sciences and Mathematics or instructor's permission. Exploration of the physical and chemical characteristics of hazardous chemicals, hazardous waste, and mixed waste materials. Their sources, handling, transportation, storage, disposal, and regulation.

CHEM 520  Advanced Inorganic Chemistry  (3 credits)

Prerequisite(s): CHEM 420 or departmental approval. Major topics include: Covalent, ionic and metallic bonding; molecular structure and polarity; Bronsted-Lowry, Lewis, and hard/soft acid and base theory; symmetry and group theory; periodic trends; structures, isomers, ligand field theory, spectra, and reactions of transition metal coordination compounds; bonding and reactions of organometallic compounds; and the biological and medicinal roles of metal ions.

CHEM 525  Bioinorganic Chemistry  (3 credits)

Prerequisite(s): CHEM 341 or instructor's permission. Exploration of the vital roles that metal atoms play in biochemical processes. Transition metal interactions with proteins will be emphasized. The course will focus on the structural, regulatory, catalytic, transport, and oxidation-reduction functions of metal containing biomolecules.

CHEM 530  Advanced Organic Chemistry  (3 credits)

Prerequisite(s): CHEM 430 or departmental approval. Structure, reactivity and mechanisms in organic chemistry: Topics include bonding, stereochemistry, aromaticity, study of reaction mechanisms and reactive intermediates, linear free energy relationships, pericyclic reactions and organic photochemistry.

CHEM 532  Organic Synthesis  (3 credits)

Prerequisite(s): CHEM 430. Detailed study of the art, methods, and the philosophy of organic synthesis beginning with a review of classical and modern synthetic methods, followed by the planning theory of synthesis and culminating in a study of elegant syntheses in the literature.

CHEM 533  Biosynthesis of Natural Products  (3 credits)

Prerequisite(s): CHEM 430 or equivalent. A study of natural products with emphasis on the biosynthesis of primary and secondary metabolites.

CHEM 534  Separation and Analysis  (3 credits)

Prerequisite(s): CHEM 310 and CHEM 311 or equivalents. Theory and practice of major chromatographic and spectroscopic methods; including GC, HPLC, GC-MS, LC-MS/MS, FTIR, DAD- UV-VIS, and NMR.

CHEM 536  Nuclear Magnetic Resonance: Theory and Practice  (3 credits)

Prerequisite(s): CHEM 310 and CHEM 311 or equivalents. A combination lecture/hands-on course utilizing the department's FT-NMR's to provide students with theoretical background and practical experience in modern 1-D and 2-D FT-NMR.

CHEM 538  Drug Design in Medicinal Chemistry  (3 credits)

Restriction(s): Matriculation into the graduate program or permission of instructor. A comprehensive course covering the design and action of pharmaceutical agents.

CHEM 540  Advanced Physical Chemistry  (3 credits)

Prerequisite(s): CHEM 341 or instructor's permission. In-depth covering of thermodynamic concepts such as state functions and chemical equilibrium, calorimetry, molecular interactions, activities. Introduction to quantum chemistry.

CHEM 542  Quantum Chemistry and Spectroscopy  (3 credits)

Prerequisite(s): CHEM 540 or departmental approval. Theoretical development of quantum mechanics as applied to chemistry. Application of theoretical procedure to atomic and molecular structure and bonding. Introduction to the theory of molecular spectroscopy.

CHEM 544  Chemical Thermodynamics and Electrochemistry  (3 credits)

Prerequisite(s): CHEM 540 or departmental approval. In-depth study of classical thermodynamics. Development of thermodynamic functions describing chemical systems in equilibrium, with emphasis on systems of variable composition. Principles and application of electrochemistry, relationship of electrochemical principles to classical thermodynamics, and practical applications of electrochemistry.

CHEM 546  Chemical Spectroscopy  (3 credits)

Prerequisite(s): CHEM 341. Introduction to the theory of molecular spectroscopy.

CHEM 548  Chemical Kinetics  (3 credits)

Prerequisite(s): CHEM 341. Kinetics in its role of elucidating reaction mechanisms. Discussion of recent problems from the chemical literature including fast reactions and enzyme kinetics.

CHEM 550  Organometallic Chemistry  (3 credits)

Prerequisite(s): CHEM 420 and CHEM 430 or equivalents. The course will introduce students to organometallic chemistry, mainly involving transition metals, but also including some main group metals. The material covered will focus on the unique chemistry of these compounds and their uses in organic synthesis, material science, and as catalysts.

CHEM 560  Advanced Analytical Chemistry  (3 credits)

Prerequisite(s): CHEM 310 and CHEM 311 or departmental approval. This course builds on existing knowledge of analytical chemistry to develop a deeper understanding of how quality and quantity of data, propagation of errors, and instrumentation and laboratory protocols affect the uncertainty in measurements. This will be tied into the relevance and importance of validation of equipment and protocols and standard laboratory practices, which are discussed in light of requirements from regulatory agencies.

CHEM 570  Advanced Biochemistry  (3 credits)

Prerequisite(s): CHEM 370 or instructor's permission. Structure, function, and chemistry of proteins, carbohydrates, nucleic acids, and lipids. Analytical methods biochemists use to study metabolism, regulation, binding, and catalytic activity of biomolecules.

CHEM 574  Protein Structure  (3 credits)

Prerequisite(s): One semester of introductory Biochemistry or similar background. Primary, secondary and tertiary structure of proteins, protein structural motifs and protein structural families. Globular proteins, DNA binding proteins, membrane proteins, signal transduction systems, immune system protein structure, methods used for determination of protein structure.

CHEM 575  Enzyme Kinetics and Mechanisms  (3 credits)

Prerequisite(s): CHEM 370 or equivalent. The following properties of enzymes are considered: structure, specificity, catalytic power, mechanism of action, multienzyme complexes, kinetics, regulation, and multienzyme systems.

CHEM 576  Lipid Biochemistry  (3 credits)

Prerequisite(s): CHEM 370 or equivalent. Chemistry of plant and animal lipids, their occurrence, metabolism, and industrial uses.

CHEM 577  Nucleic Acid Biochemistry  (3 credits)

Prerequisite(s): CHEM 370 or equivalent. This course will present fundamental aspects of nucleic acid biochemistry including structure and biological function and will be organized according to a systematic consideration of techniques used in the study of nucleic acids. Current literature and key topics such as protein-DNA, protein-drug complexes and nucleic acid repair mechanisms will be considered.

CHEM 578  Biochemistry Laboratory Techniques  (3 credits)

Prerequisite(s): CHEM 370 or equivalent. Fundamental techniques used to isolate, characterize, and study nucleic acids, proteins, carbohydrates, and lipids. Theory and application of buffers, spectrophotometry, tissue fractionation, centrifugation, extraction, chromatographic separations, electrophoresis, radioactivity, enzyme purification and dinetics, enzymatic assays, NMR and MS structure determination.

CHEM 579  Biomolecular Assay Development  (3 credits)

Prerequisite(s): CHEM 370 or instructor's permission. This course will provide the student with hands-on experience of state of the art techniques used for drug discovery research in the pharmaceutical industry. These techniques include assay development for high throughput screening and molecular docking methods for lead discovery. Using these techniques will allow the student to understand the drug discovery process, which includes a dialogue between crystallographers, medicinal chemists, biochemists, and biologists.

CHEM 582  Biochemical Pharmacology  (3 credits)

Prerequisite(s): CHEM 370 and CHEM 371. How drugs interact with, and influence biochemical pathways relevant to disease in the whole organism. Topics covered in this course deal with a review of fundamental concepts in biochemistry relevant to drug discovery, the process of drug discovery and specific examples of drug interactions with biochemical pathways and how they impact human disease.

CHEM 590  Special Topics in Advanced Chemistry  (3 credits)

Prerequisite(s): CHEM 341 or instructor's permission. An in-depth study of selected areas in either analytical, inorganic, organic or physical chemistry, with special emphasis upon recent developments in the field. May be repeated three times for a maximum of 12 credits as long as the topic is different each time.

CHEM 595  Graduate Research  (1-6 credits)

Restriction(s): Matriculation into a CSAM graduate program; instructor's permission. Directed individual laboratory investigation under guidance of faculty advisor. May be repeated for a maximum of 6 credits.

CHEM 598  Graduate Literature Search  (1 credit)

Prerequisite(s): Completion of 18 semester hours of 500-level courses in the graduate program. Development of and investigation of a topic from the current chemical literature. Selection and refinement of a topic. Collection and preparation of resources and materials and development of an outline in preparation of writing a literature report and giving a formal seminar on the literature search. This course cannot be taken by students electing the Research/Thesis option for their graduate program. This course may be repeated once for a maximum of 2 credits.

CHEM 599  Graduate Seminar  (1 credit)

Prerequisite(s): CHEM 598. An individual, non-experimental investigation and a formal presentation of scientific literature.

CHEM 698  Master's Thesis  (3 credits)

Prerequisite(s): Departmental approval. Independent research project done under faculty advisement. Students must follow the MSU Thesis Guidelines, which may be obtained from the Graduate School. Students should take CHEM 699 if they don't complete CHEM 698 within the semester.

CHEM 699  Master's Thesis Extension  (1 credit)

Prerequisite(s): CHEM 698. Continuation of Master's Thesis Project. Thesis Extension will be graded as IP (in Progress) until thesis is completed, at which time a grade of Pass or Fail will be given.